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Geodon (Ziprasidone) is used to treat severe mental disorders.

Drug Name

Geodon (Ziprasidone)

Drug Uses

Geodon is used to treat severe mental disorders like schizophrenia, which are characterized by distorted thoughts, perceptions, and emotions. Geodon helps manage schizophrenia's "positive symptoms," (visual and auditory hallucinations, and delusions) and may also help in treating the "negative symptoms" of schizophrenia (social withdrawal, apathy, lack of motivation, and an inability to experience pleasure). Geodon is also used to treat acute bipolar mania, including manic and mixed episodes.

How Taken

Geodon usually is taken twice a day. The usual starting dose is 20 mg twice daily. The dose may be increased over time to achieve the desired effect. Geodon should be taken with food (for example, shortly after a meal) since when taken on an empty stomach, much less geodon is absorbed.

Drug Class and Mechanism

Geodon is an oral and injectable drug that is used for treating psychoses, for example, schizophrenia. Although the mechanism of geodon action is not known, like other anti-psychotics, it inhibits communication between nerves of the brain. It does this by blocking receptors on the nerves for several neurotransmitters, the chemicals that nerves use to communicate with each other. It is thought that the beneficial effect of geodon is due to its blocking of dopamine and serotonin receptors. It also inhibits the re-uptake of serotonin and norepinephrine by nerves in the brain like some anti-depressant drugs. Geodon is associated with little or no weight gain, a feature that distinguishes it from other anti-psychotic drugs. Similarly, geodon is unique among anti-psychotic drugs in that it does not increase cholesterol levels.

Missed Dose

Continue to take this medicine even if you feel well. Do not miss any doses. If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


Capsules should be stored at room temperature, between 15 and 30 degrees C (59-86 degrees F).